Patients with microphthalmia (MAC) have an increased risk of congenital heart disease (CHD) and other malformations, according to a new study. The disease, also known as Small Eye Syndrome, causes eye defects and is only seen in about two of every 10,000 births. Researchers from Albert Einstein Medical Center examined 225 cases and collected data about malformations associated with MAC. A subanalysis was performed to determine if a correlation between CHD and malformations was predictable. Researchers found that the incidence of CHD was significantly higher in patients with MAC, than it was in the general population. Furthermore, if CHD was present in patients with MAC, the incidence of malformations was significantly increased.
CHEST 2006 abstract briefs
Contact: Jennifer Stawarz
American College of Chest Physicians
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